From a DNA strand coded as 5' ATG CCC GTG TTA AAA TGT GGG ATC CCC GGT GTG CCC TTA 3', what is the sequence of the antisense strand (3' to 5')?

To determine the sequence of the antisense strand of a given DNA strand, you need to understand the complementary base pairing that occurs in DNA. Adenine (A) pairs with thymine (T), and cytosine (C) pairs with guanine (G). The provided DNA strand is read from the 5' to 3' direction, and to find the antisense strand, which is the complement, you need to read the bases in the reverse direction (3' to 5').

The original strand is:

5' ATG CCC GTG TTA AAA TGT GGG ATC CCC GGT GTG CCC TTA 3'

When you match each base to its complementary counterpart, you do the following transformations:

• A ↔ T

• T ↔ A

• C ↔ G

• G ↔ C

Applying these transformations to the original strand results in:

• 3' TAC GGG CAC AAT TTT ACA CCC TAG GGG CCA CAC GGG AAT 5'

The correct answer demonstrates the reverse orientation of the strand as well as the correct pairing of the bases. Thus, the antisense strand has been constructed correctly according to the rules of complementary base pairing,